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Frequently Asked Questions

Here are the answers to many common questions about Serzone (nefazodone HCl). You may select a specific question or browse through them all.

What is Serzone (nefazodone HCl)?
Why has my doctor chosen Serzone for me?
What can I expect from Serzone treatment?
How long will I be on Serzone?
How can I get into the routine of taking my Serzone?
Will I experience any side effects?
Are there any foods, drinks, medicines or activities I should avoid?
Who should not take Serzone?

What is Serzone (nefazodone HCl)?
Serzone is an effective
antidepressant medication, that is indicated for the treatment of depression.

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Why has my doctor chosen Serzone for me?
Serzone is effective to treat depression with or without depression-associated anxiety symptoms and sleep problems. These symptoms usually show improvement within 1 to 2 weeks of treatment but full antidepressant effect may take several weeks.

Also, Serzone is associated with minimal sexual problems and minimal weight changes, and common side effects of many other antidepressant medications.

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What can I expect from Serzone treatment?
Serzone is usually taken twice a day. Typically, doctors start Serzone at a low dose and gradually increase the dose over time. This gradual increase can help minimize side effects while still providing much needed symptom relief.

Serzone is associated with minimal sexual problems and doesn’t cause significant weight changes, common side effects of many other antidepressant medications.

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How long will I be on Serzone?
Antidepressants are usually prescribed for 6 months to one year.

Remember, depression is often a long-term condition that may require long-term treatment.

Like other antidepressants, if your Serzone treatment is stopped too soon, your symptoms of depression may not get completely better. Or, if your symptoms have been resolved, they may return.

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How can I get into the routine of taking my Serzone?
Many people find it helpful to link taking their medicine to something they do every day—like brushing their teeth.

Another way is to set up a daily chart so that you can check off the times when you’ve taken the medicine.

Some people buy a weekly pillbox from their local pharmacy and fill it with the medicine they’ll need for the week.

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Will I experience any side effects?
In general, most people tolerate Serzone (nefazodone HCl).

The most commonly reported side effects are dry mouth, sleepiness, nausea, dizziness, constipation, weakness, lightheadedness, confusion, abnormal and blurred vision.

Please see the Patient Information enclosed with your samples.

Although side effects may be bothersome, they are often a sign that your body is adjusting to the medication. If you are concerned about any side effects you experience, talk with your doctor.

Do not change the amount or stop taking the medication on your own.

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Are there any foods, drinks, medicines or activities I should avoid? Who should not take Serzone?
Be sure to tell your doctor about any other medications you are taking.

Serzone should not be taken by those who are taking Seldane� (terfenadine), Hismanal (astemizole), Propulsid (cisapride), Tegretol (carbamazepine), or Orap (pimozide).

It is not recommended for those taking monoamine oxidase inhibitors (MAOIs) or Halcion (triazolam).

A dosage reduction of Xanax (alprazolam) is recommended when used with Serzone.

As with all antidepressants, you should avoid alcohol while taking Serzone.

Use caution when operating a car or other machinery until you are certain Serzone does not have an adverse affect on your thinking and motor skills.

Women who are pregnant or nursing should not use any antidepressant without first consulting with their doctor.

Seldane is a registered trademark of Aventis Pharmaceuticals. Hismanal and Propulsid are registered trademarks of Janssen Pharmaceutica Inc. Orap is a registered trademark of Gate Pharmaceuticals. Halcion and Xanax are registered trademarks of Pharmacia & Upjohn.

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